- Raw material availability,
- Allergen concerns,
- Environmental pollution caused by the process of extracting chitin from shellfish.
- Quercetin: a bioflavonoid that is naturally found in fruit and vegetables, particularly in apples. This bioflavonoid is a potent antioxidant and may also play a part in inhibiting the production and release of histamines.
- Ginger: a popular spice, often used alongside glucosamine.
- Rose hips: naturally rich in vitamin C and contribute to normal collagen formation for the normal function of cartilage.
- MSM: as a naturally occurring sulphur compound, MSM is one of the major building blocks of glycosaminoglycans (GAGs), a key component of cartilage.